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We are going to try to bring you near-daily updates on COVID-19. There is a firehose of information and most of us are too busy to read and digest it all. Note: If you are listening to these more than a few days in the future, please beware that information may have changed and check subsequent episodes.

Also, please check out Brief19.com for the latest research and policy updates regarding COVID-19

Cytokine Storm – Mehta et al describe cytokine storm or secondary hamophagocytic lymphohistiocytosis (sHLH), a hyperinflammatory state, which characterizes some presentations of critical COVID-19.

The Society of Critical Care Medicine (SCCM) updated their COVID 19 guidelines (reviewed here), in which high flow nasal cannula (HFNC) was recommended. HFNC is an aerosol generating form of oxygenation so we review some of the data around this, including an article by Will Loh et al.

Asymptomatic transmission and basic reproductive number (Ro). Aguilar et al.