Monkeypox

Apple Podcasts, Spotify

Updated July 29, 2022

In a three-part series, we review the current status of the monkeypox outbreak.

Episode 1: Virology, Transmission, Epidemiology

Episode 2: Clinical Manifestations, Treatment, Vaccination

Episode 3: The TLDR Quick Summary

Patel A et al. Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series. BMJ. 2022 Jul 28;378:e072410. PMID: 35902115.

Thornhill JP et al. Monkeypox Virus Infection in Humans across 16 Countries – April-June 2022. N Engl J Med. 2022 Jul 21. doi: 10.1056/NEJMoa2207323. PMID: 35866746.

References: https://www.cdc.gov/poxvirus/monkeypox/clinicians/treatment.html
Reference: https://www.cdc.gov/poxvirus/monkeypox/clinicians/smallpox-vaccine.html#pre-exposure

Hemorrhoids

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There are practice-changing updates in the guidelines from the World Society of Emergency Surgery (WSES) and American Association for the Surgery of Trauma (AAST), found here. In this podcast, we review hemorrhoids and management.

Perera N, Liolitsa D, Iype S, Croxford A, Yassin M, Lang P, Ukaegbu O, van Issum C. Phlebotonics for haemorrhoids. Cochrane Database Syst Rev. 2012 Aug 15;(8):CD004322. doi: 10.1002/14651858.CD004322.pub3. PMID: 22895941.
Cavcić J, Turcić J, Martinac P, Mestrović T, Mladina R, Pezerović-Panijan R. Comparison of topically applied 0.2% glyceryl trinitrate ointment, incision and excision in the treatment of perianal thrombosis. Dig Liver Dis. 2001 May;33(4):335-40. doi: 10.1016/s1590-8658(01)80088-8. PMID: 11432512
Cavcić J, Turcić J, Martinac P, Mestrović T, Mladina R, Pezerović-Panijan R. Comparison of topically applied 0.2% glyceryl trinitrate ointment, incision and excision in the treatment of perianal thrombosis. Dig Liver Dis. 2001 May;33(4):335-40. doi: 10.1016/s1590-8658(01)80088-8. PMID: 11432512.

The End of Diphenhydramine

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Diphenhydramine and other first-generation antihistamines are ubiquitous in medicine cabinets across the globe. Clinicians commonly recommend or administer diphenhydramine (Benadryl) for a variety of diseases – anaphylaxis, allergic reactions, urticaria, benign headaches/migraines, and as a sleep aid. However, professional societies have recommended against many of these indications for decades and, in other cases, there are safer alternatives. For more reading and references, see this article in ACEPnow.

For more in-depth reviews: Podcast on anaphylaxis and podcast on urticaria