COVID-19 – Literature Update

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We are bringing you near-daily updates on COVID-19. There is a firehose of information and most of us are too busy to read and digest it all. Note: If you are listening to these more than a few days in the future, please beware that information may have changed and check subsequent episodes. This episode was recorded May 15, 2020

Halfmann et al NEJM 2020
Holmes et al Lancet 2020
Knight et al – pre-print
See prior podcast on vertical transmission in pregnancy and pregnancy and breastfeeding in COVID
podcast on PIMSTSS
Toubiana et al pre-print
Verdoni et al Lancet 2020
Begley et al. Anaesthesia 2020
Meredith et al pre-print

COVID-19: Pediatric multisystem inflammatory syndrome temporally associated with COVID-19

Apple Podcasts or Listen Here

We are bringing you near-daily updates on COVID-19. There is a firehose of information and most of us are too busy to read and digest it all. Note: If you are listening to these more than a few days in the future, please beware that information may have changed and check subsequent episodes. This episode was recorded May 9, 2020

Royal College of Paediatrics and Child Health
Riphagen et al. Lancet 2020

COVID-19: Convalescent Plasma

Apple Podcasts or Listen Here

We are bringing you near-daily updates on COVID-19. There is a firehose of information and most of us are too busy to read and digest it all. Note: If you are listening to these more than a few days in the future, please beware that information may have changed and check subsequent episodes. This episode was recorded May 6, 2020

Rajendran et al (poor quality systematic review)
Shen et al
Zhang et al
Ye et al
Ahn et al
Duan et al
Biegel et al (influenza A RCT)

COVID-19: Antibody Testing

Apple Podcasts or Listen Here

We are bringing you near-daily updates on COVID-19. There is a firehose of information and most of us are too busy to read and digest it all. Note: If you are listening to these more than a few days in the future, please beware that information may have changed and check subsequent episodes. This episode was recorded May 2, 2020

Zhao J, Yuan Q, Wang H, et al. Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019. Clin Infect Dis. 2020;
IDSA COVID-19 antibody primer
IDSA COVID-19 antibody primer
Crook et al. MedRxiv pre-print

COVID-19: Excess Mortality and Out of Hospital Cardiac Arrest

Apple Podcasts or Listen Here

We are bringing you near-daily updates on COVID-19. There is a firehose of information and most of us are too busy to read and digest it all. Note: If you are listening to these more than a few days in the future, please beware that information may have changed and check subsequent episodes. This episode was recorded 4/29/20

Baldi et al. NEJM April 2020 doi: 10.1056/NEJMc2010418

COVID-19: Cutaneous Manifestations and “COVID toes”

Apple Podcasts or Listen Here

We are bringing you near-daily updates on COVID-19. There is a firehose of information and most of us are too busy to read and digest it all. Note: If you are listening to these more than a few days in the future, please beware that information may have changed and check subsequent episodes. This episode was recorded 4/28/20

Recalcati – general overview of 18 cases of cutaneous manifestations in COVID-19
Manalo – Describes a case of transient livedo reticularis
Fernandez-Nieto 
Piccolo et al
Duong et al
Alrantham, Aldaraji
Recalcati et al
Kolivras et al
Zhang et al.
Zhang et al

COVID-19: Autopsy Studies & Venous Thromboembolism

Apple Podcasts or Listen Here

We are bringing you near-daily updates on COVID-19. There is a firehose of information and most of us are too busy to read and digest it all. Note: If you are listening to these more than a few days in the future, please beware that information may have changed and check subsequent episodes. This episode was recorded 4/26/20

Carsana et al 
Dolhnikoff et al
Barton et al
Fox et al
Obi et al

COVID-19: Self proning oxygenation

Apple Podcasts or Listen Here

We are bringing you near-daily updates on COVID-19. There is a firehose of information and most of us are too busy to read and digest it all. Note: If you are listening to these more than a few days in the future, please beware that information may have changed and check subsequent episodes. This episode was recorded 4/23/20

Caputo, Strayer, Levitan Academic Emergency Medicine 2020 (in press)

COVID-19: The Paradigm Shift From Early Intubation

Apple Podcasts or Listen Here

We are bringing you near-daily updates on COVID-19. There is a firehose of information and most of us are too busy to read and digest it all. Note: If you are listening to these more than a few days in the future, please beware that information may have changed and check subsequent episodes.

We are joined by Dr. Rory Spiegel (@EMNerd_) who blogs at EMcrit and discuss why many places have switched from an “intubate early” paradigm in COVID-19 to a “try not to intubate” protocol.

Example of respiratory protocols we discuss (collection at REBEL EM)

More discussion on this article here
Wang et al. The experience of high-flow nasal cannula
in hospitalized patients with 2019 novel coronavirus-infected pneumonia in two hospitals of Chongqing, ChinaAnn Intensive Care. 2020 10(37)
We discuss several articles including:
Sun et al. Ann. Lower mortality of COVID-19 by early recognition and intervention: experience from Jiangsu Province. Intensive Care (2020) 10:33
Ding et al. Efficacy and safety of early prone positioning combined with HFNC or NIV in moderate to severe ARDS: a multi-center prospective cohort study. Critical Care. 24(28). 2020
Scaravilli V, Grasselli G, Castagna L, et al. Prone positioning improves oxygenation in spontaneously breathing nonintubated patients with hypoxemic acute respiratory failure: A retrospective study. J Crit Care 2015;30(6):1390–4.
Check out podcast here

COVID-19: Thrombosis (VTE guidelines & MI)

Apple Podcasts or Listen Here

We are bringing you near-daily updates on COVID-19. There is a firehose of information and most of us are too busy to read and digest it all. Note: If you are listening to these more than a few days in the future, please beware that information may have changed and check subsequent episodes.

This post builds on our prior podcast episode that was a more in-depth review of hypercoagulability in COVID-19.

JACC COVID-19 guidelines
Bangalore. NEJM. 2020. doi: 10.1056/NEJMc2009020