Steroids in COVID-19

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We are bringing you near-daily updates on COVID-19. There is a firehose of information and most of us are too busy to read and digest it all. Note: If you are listening to these more than a few days in the future, please beware that information may have changed and check subsequent episodes. This episode was recorded September 3, 2020.

We have previously covered the RECOVERY trial’s reporting of the use of dexamethasone in hospitalized patients with COVID-19. In the wake of those results, several ongoing trials of steroids in COVID-19 were halted, due to concerns about loss of equipoise. Three of these trials were published in JAMA on September 2, 2020 in conjunction with a meta-analysis from the WHO REACT working group.

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